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Tuesday, February 5, 2019

Optimization of Ritalin for more Effective Results Essay -- Methylphen

methylphenidate (methylphenidate) optimisationmethylphenidate PillsAbstractAttention-deficit hyperactivity affection (hyperkinetic syndrome) is currently the dominating psychiatricdisorder be in children. The creation of the drug Ritalin based on the soupconmethylphenidate in the early 90s sparked a far-flung use of this psycho stimulant, which stillremains as single of the closely popular drugs used to counteract the symptoms of ADHD. Myultimate goal in this investigate project is to design analogs for the drug Ritalin in the hopes ofdiscovering a more than effective version of this medication. Through research, it can be cogitatethat no(prenominal) the analogs suggested are suitable candidates for new drugs based on the results. existenceWith 3-5 percent of school children today diagnosed with attention-deficit hyperactivitydisorder (ADHD), ADHD has been reported to floor for 50 percent of the child psychiatricpopulation seen at the clinic. Methylphenidate ( think 1)se rves as the dominant drug used in medicationscounteracting the symptoms of ADHD. (1) Among thosemedications, Ritalin is currently prescribe for daily use to1.5 million school children in the linked States, do itone of the most widely used prescription medicationstoday. (2) The optimization of Ritalin is of utmostimportance and will therefore, be the topic of this project.Scientists entrust that ADHD is caused by an imbalance between dopaminergic,noradrenergic and serotonergic neurotransmitter systems. However, this theory remains perplexing collectable to an insufficient amount of evidence. Methylphenidates mechanism of action,Fig. 1 MethylphenidateMolecular Structurewhich is based on dopamine synaptic aspiration inhibition,essentially allows it to binds to ... ... Wiley & Sons, Ltd. (1997) 29 July 20082) Ritalin Fast Facts. Do It at present Foundation. 29 July 2008. come in 1 United States Environmental Protection Agency. July 28 2008.figure 2 Medscape. July 28 2008.title p icture Wikimedia. July 28 2008.figure 4 Wikipedia. July 28 2008. figure 5 Wikipedia. July 28 2008. %28primary%29-skeletal.pngfigure 8 Wikipedia. July 28 2008. svg Optimization of Ritalin for more Effective Results Essay -- MethylphenRitalin (Methylphenidate) OptimizationRitalin PillsAbstractAttention-deficit hyperactivity disorder (ADHD) is currently the dominating psychiatricdisorder found in children. The creation of the drug Ritalin based on the moleculeMethylphenidate in the early 90s sparked a widespread use of this psycho stimulant, which stillremains as one of the most popular drugs used to counteract the symptoms of ADHD. Myultimate goal in this research project is to design analogs for the drug Ritalin in the hopes ofdiscovering a more effective version of this medication. Through research, it can be concludedthat none the analogs suggested are suitable candidates for new drugs based on the results.IntroductionWith 3-5 percent of school children today diagno sed with attention-deficit hyperactivitydisorder (ADHD), ADHD has been reported to account for 50 percent of the child psychiatricpopulation seen at the clinic. Methylphenidate (figure 1)serves as the dominant drug used in medicationscounteracting the symptoms of ADHD. (1) Among thosemedications, Ritalin is currently prescribed for daily use to1.5 million school children in the United States, making itone of the most widely used prescription medicationstoday. (2) The optimization of Ritalin is of utmostimportance and will therefore, be the topic of this project.Scientists believe that ADHD is caused by an imbalance between dopaminergic,noradrenergic and serotonergic neurotransmitter systems. However, this theory remainsquestionable due to an insufficient amount of evidence. Methylphenidates mechanism of action,Fig. 1 MethylphenidateMolecular Structurewhich is based on dopamine synaptic uptake inhibition,essentially allows it to binds to ... ... Wiley & Sons, Ltd. (1997) 29 July 200 82) Ritalin Fast Facts. Do It Now Foundation. 29 July 2008.figure 1 United States Environmental Protection Agency. July 28 2008.figure 2 Medscape. July 28 2008.title picture Wikimedia. July 28 2008.figure 4 Wikipedia. July 28 2008. figure 5 Wikipedia. July 28 2008. %28primary%29-skeletal.pngfigure 8 Wikipedia. July 28 2008. svg

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